GLEEVEC is often associated with edema and, occasionally, serious fluid retention. Severe fluid retention was reported in 9% to 13.1% and 2.5% to 11% of patients taking GLEEVEC for GIST and CML, re...
THE RIGHT SUPPORT AT THE RIGHT TIME
To learn more about what the Novartis Oncology Patient Support Program can offer your patients, call 1-800-282-7630 or visit www.HCP.Novartis.com/Access/.
You have the option to keep your patients on branded GLEEVEC if you decide that it is the right option for their treatment.
With every new prescription, include “Dispense as Written” (“DAW”) or your state or territory’s required language. Even if you’ve written a prescription with “DAW” in the past, it may not apply to a new prescription. Without this language, the pharmacist may substitute a generic form of GLEEVEC.
If you are e-prescribing, help ensure that automatic generic substitution does not occur by selecting branded “GLEEVEC” from the medications list. This process may vary based on the EHR platform.
What are my options if I want a patient to receive branded GLEEVEC vs a generic?
If you decide that branded GLEEVEC is right for your patient, you can take these steps to ensure they receive it at every refill:
Include "Dispense as Written" (“DAW”), or your state or territory's required language, on the prescription.
Inform your patient that while they are at the pharmacy, or while placing a prescription mail order, they should verify with the pharmacist that the doctor's preference is for branded GLEEVEC.
A patient's insurance plan is an important factor in determining their out-of-pocket expenses for branded and generic medications. In addition, costs can be affected by statutes related to a state or territory’s specific DAW guidelines. Note that there may be a difference in cost between branded GLEEVEC and generics.
Will all pharmacies stock branded GLEEVEC?
Novartis is committed to making sure branded GLEEVEC is available, but we can’t control what medications individual pharmacies stock. If a patient’s pharmacy doesn’t stock branded GLEEVEC, they can ask the pharmacy to special order it, which usually can be delivered in a day.
What if my patient's insurance provider changes the status of GLEEVEC, and this medication is no longer covered or they are denied at the pharmacy?
If this occurs, your patient can initiate an appeal with their insurance provider. You and your patient can learn more about the steps required to file an appeal by calling 1-800-282-7630. Please note that an appeal does not guarantee reinstatement of coverage and if successful, a patient's appeal may result in a change in out-of-pocket costs from what they have paid in the past.
Who provides a generic form of GLEEVEC?
In February 2016, the first FDA-approved generic form of GLEEVEC became available in the United States. Since that time, other manufacturers have been granted approval to produce generic forms of GLEEVEC.
What is my patient's out-of-pocket cost for a generic form of GLEEVEC?
Medication costs for patients can vary based on a variety of factors, such as insurance coverage and/or government assistance programs, and the costs set by the manufacturer.
Will the pharmacist switch a patient's branded GLEEVEC prescription?
The pharmacy may substitute a generic in place of branded GLEEVEC, depending on individual state laws. If you and your patient choose to stay on branded GLEEVEC, you may do so by including "Dispense as Written" (“DAW”), or your state or territory's required language, on the prescription.
If a patient receives a generic form of GLEEVEC, will it look the same as GLEEVEC?
A generic will appear different from GLEEVEC in characteristics such as pill shape, size, and color. In addition, now that there are multiple generic versions of GLEEVEC, pill appearance may vary from month to month, depending on which generic the pharmacy has in stock. However, even though the generic pill may appear different, the FDA requires that generic medications contain the same active ingredient as the brand name, and that they function comparably in the human body.
Has the out-of-pocket cost of branded GLEEVEC changed now that multiple generics are available?
A patient’s out-of-pocket costs may change based on their insurance plan design, or from other factors, which can change throughout the year. Novartis plans to continue financial support for eligible patients (including a $10 co-pay* offer for eligible, commercially insured patients). Limitations apply. See full terms and conditions. Other financial assistance may also be available.
Can the GLEEVEC $10 Co-Pay* Card be used to cover the cost of generics?
No. The GLEEVEC $10 Co-Pay* Card is only available to eligible, commercially insured patients to cover the cost of their branded GLEEVEC prescription.
Are there co-pay cards available for generic forms of GLEEVEC?
Please contact the drug manufacturers with questions related to generic imatinib mesylate.
*Limitations apply. This offer is only available to patients with private insurance. The program is not available for patients who are enrolled in Medicare, Medicaid, or any other federal or state health care program or for Massachusetts or California residents. Patient pays first $10 co-pay on a 30-day supply, and the program will pay up to $10,630 per 30-day supply up to an annual maximum of $30,000. Novartis reserves the right to rescind, revoke, or amend this program without notice. For full Terms and Conditions, visit www.CoPay.NovartisOncology.com or call 1-877-577-7756.
Encourage your patients to find out if they are eligible to enroll in the Universal Co-pay Program by visiting www.CoPay.NovartisOncology.com or calling 1-877-577-7756.
GLEEVEC® (imatinib mesylate) tablets are indicated for:
Important Safety Information
Common Side Effects of GLEEVEC Tablets
*For more detailed study information, please see full Prescribing Information.
†Numbers indicate the range of percentages in 4 studies among patients with newly diagnosed Ph+ CML, patients in blast crisis, in accelerated phase, and in the chronic phase after failure of interferon-alpha therapy.